From the airport
Taxi: It´s a 20 - 25 minutes trip and costs around 695 CZK.
Bus: You can take the bus line 100, which departs every 15 minutes, from Prague Airport to get to the station "Zlicin". From there take the metro line B (yellow line) for the station "Andel". You can reach the hotel in a walking distance from about 10 minutes. It's a 60 minutes trip.
You can choose between a single ticket (32 CZK), a day ticket (110 CZK) or a ticket for three days (310 CZK). Within the ticket price, you can take the train and the bus in Prague.